South America is a huge continent with many exciting and diverse ports of call. Like North America, cruise travelers can visit South America from three oceans--the Atlantic, the Pacific, or the Caribbean. South America can be a long flight, but covers only three time zones. The far eastern coast of Brazil is three hours ahead of Eastern Standard Time, Buenos Aires is two hours different, and the western coast of South America is on Eastern Standard Time.
Some cruisers visit South America on their way to Antarctica for a cruise. Here is a Map of Antarctica.